Cerebral perfusion pressure thresholds in TBI

CPP target range: 50 – 70 mm Hg

Patients with intact pressure  auto-regulation tolerate higher target CPP

Based on:

Aggressive attempts to maintain CPP > 70 mm Hg risk pulmonary oedema, cardiac failure, ARDS (Level II evidence)

CPP < 50 mm Hg should be avoided (Level III evidence)

Brain Trauma Foundation Guidelines.

https://www.braintrauma.org/coma-guidelines/searchable-guidelines/

 

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